Santa Clara High School competes in the Tri-County Athletic Association.  Over the years, Santa Clara High School athletes and teams have won numerous State, Section, and League Titles.

California State Championships

• 1989- Boys Basketball
• 1990- Boys Basketball
• 1997- Aaron Sharp, Cross Country
• 1999- Boys Basketball
• 2000- Boys Cross Country
• 2003- Tony Arredondo, Cross Country

California State Runners Up

• 1983- Boys Basketball
• 1991- Boys Basketball
• 2002- Boys Cross Country

Southern California Championships

• 1983- Boys Basketball
• 1989- Boys Basketball
• 1991- Boys Basketball
• 1999- Boys Basketball

Southern California Runner Up

• 1989- Girls Basketball
• 1991- Boys Basketball
• 2002- Boys Cross Country
• 2011- Girls Basketball

CIF-Southern Section Championships

• 1951- Baseball
• 1959- Boys Basketball
• 1960- Boys Basketball, Baseball
• 1961- Boys Basketball
• 1963- Football, Boys Basketball
• 1964- Boys Basketball
• 1965- Football
• 1974- Gordon Kurz: 180 Low Hurdles, Gordon Kurz: Long Jump, David Laut: Shot Put,
• 1975- David Laut, Shot Put, Track and Field
• 1980- Boys Basketball
• 1981- Boys Basketball
• 1982- Jeff Conway: 400 M, Track and Field
• 1983- Boys Basketball
• 1985- Boys Basketball
• 1986- Girls Basketball
• 1989- Girls Basketball, Boys Basketball
• 1990- Boys Basketball, Taryn Tarver: Girls Long Jump, Track and Field
• 1991- Boys Basketball
• 1992- Boys Basketball
• 1997- Boys Basketball
• 1999- Boys Basketball
• 2000- Boys Cross Country
• 2003- Tony Arredondo, Cross Country
• 2007- Football
• 2011- Girls Basketball, Christina Gomez: 100 yd Backstroke, Swimming

CIF-Southern Section Runner Up

• 1962- Boys Basketball
• 2002- Boys Cross Country
• 2009- Girls Basketball
• 2010- Boys Soccer

League Championships (Tri-Valley and Frontier Leagues)

• 1950- Baseball
• 1951- Baseball
• 1953- Baseball
• 1954- Baseball
• 1957- Boys Basketball
• 1958- Football, Boys Basketball
• 1959- Boys Basketball, Baseball
• 1960- Boys Basketball, Baseball
• 1961- Football, Boys Basketball
• 1962- Boys Basketball
• 1963- Football, Boys Tennis, Baseball, Track and Field
• 1964- Baseball
• 1965- Football, Boys Basketball, Baseball
• 1966- Football
• 1967- Football, Boys Basketball
• 1968- Football, Wrestling, Baseball
• 1969- Football, Boys Basketball
• 1974- Girls Volleyball, Boys Basketball
• 1975- Cross Country
• 1976- Girls Volleyball, Boys Basketball, Girls Basketball
• 1977- Girls Volleyball, Girls Basketball, Boys Tennis, Baseball, Softball
• 1978- Girls Volleyball, Girls Basketball, Boys Basketball
• 1979- Boys Basketball
• 1982- Boys Basketball
• 1983- Boys Basketball, Girls Basketball
• 1984- Girls Basketball
• 1985- Football, Boys Basketball, Girls Basketball, Baseball
• 1986- Boys Basketball
• 1987- Boys Basketball, Girls Basketball
• 1988- Football, Boys Basketball, Girls Basketball, Baseball
• 1989- Football, Boys Basketball, Girls Basketball
• 1990- Boys Basketball
• 1991- Boys Basketball, Girls Soccer
• 1992- Boys Basketball, Girls Basketball, Girls Soccer, Baseball
• 1993- Boys Basketball, Girls Soccer
• 1994- Boys Basketball, Girls Soccer
• 1995- Girls Volleyball, Boys Basketball, Girls Soccer
• 1996- Boys Basketball, Girls Soccer
• 1997- Boys Basketball
• 1999- Boys Basketball
• 2002- Boys Cross Country
• 2003- Boys Cross Country
• 2006- Football
• 2007- Football
• 2009- Girls Basketball
• 2010- Girls Basketball, Boys Soccer
• 2011- Girls Basketball, Softball
• 2013- Football, Baseball